AT5G63920 (AtTOP3alpha, TOP3A)

Aliases : AtTOP3alpha, TOP3A

Description : topoisomerase 3alpha

Gene families : OG0002141 (OrthoFinder output from all 47 species) Phylogenetic Tree(s): OG0002141_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AT5G63920

Target	Alias	Description	ECC score	Gene Family Method	Actions
Sacu_v1.1_s0024.g009187	No alias	not classified & original description: CDS=1-561	0.03	OrthoFinder output from all 47 species
Sam_g27716	No alias	topoisomerase component *(TOP3-alpha) of RTR Holliday...	0.03	OrthoFinder output from all 47 species

Type	GO Term	Name	Evidence	Source
BP	GO:0000712	resolution of meiotic recombination intermediates	IMP	Interproscan
BP	GO:0003006	developmental process involved in reproduction	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	ISS	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	ISS	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	ISM	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	None	Extended
BP	GO:0006261	DNA-templated DNA replication	RCA	Interproscan
BP	GO:0006265	DNA topological change	ISS	Interproscan
BP	GO:0006268	DNA unwinding involved in DNA replication	ISS	Interproscan
BP	GO:0006270	DNA replication initiation	RCA	Interproscan
BP	GO:0006275	regulation of DNA replication	RCA	Interproscan
BP	GO:0006281	DNA repair	IMP	Interproscan
BP	GO:0006304	DNA modification	None	Extended
BP	GO:0006305	DNA alkylation	None	Extended
BP	GO:0006306	DNA methylation	RCA	Interproscan
BP	GO:0006479	protein methylation	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0007059	chromosome segregation	IMP	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008213	protein alkylation	None	Extended
BP	GO:0009892	negative regulation of metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010605	negative regulation of macromolecule metabolic process	None	Extended
BP	GO:0010629	negative regulation of gene expression	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
BP	GO:0016570	histone modification	None	Extended
BP	GO:0016571	histone methylation	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0018022	peptidyl-lysine methylation	None	Extended
BP	GO:0018193	peptidyl-amino acid modification	None	Extended
BP	GO:0018205	peptidyl-lysine modification	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0022402	cell cycle process	None	Extended
BP	GO:0022414	reproductive process	None	Extended
BP	GO:0031047	RNA-mediated gene silencing	RCA	Interproscan
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0032259	methylation	None	Extended
BP	GO:0032392	DNA geometric change	None	Extended
BP	GO:0032502	developmental process	None	Extended
BP	GO:0032508	DNA duplex unwinding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034968	histone lysine methylation	None	Extended
BP	GO:0036211	protein modification process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0043414	macromolecule methylation	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044728	DNA methylation or demethylation	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0048449	floral organ formation	None	Extended
BP	GO:0048451	petal formation	RCA	Interproscan
BP	GO:0048453	sepal formation	RCA	Interproscan
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0048646	anatomical structure formation involved in morphogenesis	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051052	regulation of DNA metabolic process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0051567	histone H3-K9 methylation	RCA	Interproscan
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0051726	regulation of cell cycle	RCA	Interproscan
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0061647	histone H3-K9 modification	None	Extended
BP	GO:0061982	meiosis I cell cycle process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:0140640	catalytic activity, acting on a nucleic acid	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1903046	meiotic cell cycle process	None	Extended
BP	GO:1905393	plant organ formation	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
BP	GO:0000075	cell cycle checkpoint signaling	IEP	HCCA
MF	GO:0000166	nucleotide binding	IEP	HCCA
BP	GO:0000226	microtubule cytoskeleton organization	IEP	HCCA
BP	GO:0000724	double-strand break repair via homologous recombination	IEP	HCCA
BP	GO:0000725	recombinational repair	IEP	HCCA
BP	GO:0000910	cytokinesis	IEP	HCCA
BP	GO:0000911	cytokinesis by cell plate formation	IEP	HCCA
BP	GO:0002376	immune system process	IEP	HCCA
MF	GO:0003950	NAD+ ADP-ribosyltransferase activity	IEP	HCCA
MF	GO:0004672	protein kinase activity	IEP	HCCA
MF	GO:0004674	protein serine/threonine kinase activity	IEP	HCCA
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	HCCA
MF	GO:0005524	ATP binding	IEP	HCCA
CC	GO:0005874	microtubule	IEP	HCCA
CC	GO:0005876	spindle microtubule	IEP	HCCA
CC	GO:0005971	ribonucleoside-diphosphate reductase complex	IEP	HCCA
BP	GO:0006302	double-strand break repair	IEP	HCCA
BP	GO:0006310	DNA recombination	IEP	HCCA
BP	GO:0006325	chromatin organization	IEP	HCCA
BP	GO:0006338	chromatin remodeling	IEP	HCCA
BP	GO:0006468	protein phosphorylation	IEP	HCCA
BP	GO:0006471	obsolete protein ADP-ribosylation	IEP	HCCA
BP	GO:0006793	phosphorus metabolic process	IEP	HCCA
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	HCCA
BP	GO:0006955	immune response	IEP	HCCA
BP	GO:0007010	cytoskeleton organization	IEP	HCCA
BP	GO:0007017	microtubule-based process	IEP	HCCA
BP	GO:0007093	mitotic cell cycle checkpoint signaling	IEP	HCCA
BP	GO:0007129	homologous chromosome pairing at meiosis	IEP	HCCA
BP	GO:0007154	cell communication	IEP	HCCA
BP	GO:0007165	signal transduction	IEP	HCCA
BP	GO:0007166	cell surface receptor signaling pathway	IEP	HCCA
BP	GO:0007167	enzyme-linked receptor protein signaling pathway	IEP	HCCA
BP	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IEP	HCCA
BP	GO:0007267	cell-cell signaling	IEP	HCCA
BP	GO:0007389	pattern specification process	IEP	HCCA
MF	GO:0008017	microtubule binding	IEP	HCCA
MF	GO:0008094	ATP-dependent activity, acting on DNA	IEP	HCCA
BP	GO:0008283	cell population proliferation	IEP	HCCA
BP	GO:0008361	regulation of cell size	IEP	HCCA
BP	GO:0009142	nucleoside triphosphate biosynthetic process	IEP	HCCA
BP	GO:0009200	deoxyribonucleoside triphosphate metabolic process	IEP	HCCA
BP	GO:0009202	deoxyribonucleoside triphosphate biosynthetic process	IEP	HCCA
BP	GO:0009292	horizontal gene transfer	IEP	HCCA
BP	GO:0009294	DNA-mediated transformation	IEP	HCCA
BP	GO:0009607	response to biotic stimulus	IEP	HCCA
BP	GO:0009615	response to virus	IEP	HCCA
BP	GO:0009616	RNAi-mediated antiviral immune response	IEP	HCCA
BP	GO:0009799	specification of symmetry	IEP	HCCA
BP	GO:0009855	determination of bilateral symmetry	IEP	HCCA
BP	GO:0009909	regulation of flower development	IEP	HCCA
BP	GO:0009911	positive regulation of flower development	IEP	HCCA
BP	GO:0009944	polarity specification of adaxial/abaxial axis	IEP	HCCA
BP	GO:0010014	meristem initiation	IEP	HCCA
BP	GO:0010016	shoot system morphogenesis	IEP	HCCA
BP	GO:0010050	vegetative phase change	IEP	HCCA
BP	GO:0010073	meristem maintenance	IEP	HCCA
BP	GO:0010075	regulation of meristem growth	IEP	HCCA
BP	GO:0010091	trichome branching	IEP	HCCA
BP	GO:0010267	ta-siRNA processing	IEP	HCCA
BP	GO:0010564	regulation of cell cycle process	IEP	HCCA
BP	GO:0010608	post-transcriptional regulation of gene expression	IEP	HCCA
BP	GO:0010948	negative regulation of cell cycle process	IEP	HCCA
MF	GO:0015631	tubulin binding	IEP	HCCA
MF	GO:0016301	kinase activity	IEP	HCCA
BP	GO:0016310	phosphorylation	IEP	HCCA
BP	GO:0016441	post-transcriptional gene silencing	IEP	HCCA
BP	GO:0016444	somatic cell DNA recombination	IEP	HCCA
BP	GO:0016458	obsolete gene silencing	IEP	HCCA
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	HCCA
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	HCCA
MF	GO:0016763	pentosyltransferase activity	IEP	HCCA
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	HCCA
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	HCCA
MF	GO:0017076	purine nucleotide binding	IEP	HCCA
BP	GO:0023052	signaling	IEP	HCCA
BP	GO:0030422	siRNA processing	IEP	HCCA
MF	GO:0030554	adenyl nucleotide binding	IEP	HCCA
BP	GO:0031507	heterochromatin formation	IEP	HCCA
BP	GO:0031567	mitotic cell size control checkpoint signaling	IEP	HCCA
BP	GO:0032501	multicellular organismal process	IEP	HCCA
BP	GO:0032535	regulation of cellular component size	IEP	HCCA
MF	GO:0032553	ribonucleotide binding	IEP	HCCA
MF	GO:0032555	purine ribonucleotide binding	IEP	HCCA
MF	GO:0032559	adenyl ribonucleotide binding	IEP	HCCA
BP	GO:0034470	ncRNA processing	IEP	HCCA
BP	GO:0034660	ncRNA metabolic process	IEP	HCCA
BP	GO:0035194	RNA-mediated post-transcriptional gene silencing	IEP	HCCA
BP	GO:0035196	miRNA processing	IEP	HCCA
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	HCCA
MF	GO:0036094	small molecule binding	IEP	HCCA
BP	GO:0040008	regulation of growth	IEP	HCCA
BP	GO:0040029	epigenetic regulation of gene expression	IEP	HCCA
MF	GO:0043167	ion binding	IEP	HCCA
MF	GO:0043168	anion binding	IEP	HCCA
BP	GO:0043207	response to external biotic stimulus	IEP	HCCA
BP	GO:0044419	biological process involved in interspecies interaction between organisms	IEP	HCCA
BP	GO:0045087	innate immune response	IEP	HCCA
BP	GO:0045786	negative regulation of cell cycle	IEP	HCCA
BP	GO:0045787	positive regulation of cell cycle	IEP	HCCA
BP	GO:0045814	negative regulation of gene expression, epigenetic	IEP	HCCA
BP	GO:0045930	negative regulation of mitotic cell cycle	IEP	HCCA
BP	GO:0048439	flower morphogenesis	IEP	HCCA
BP	GO:0048518	positive regulation of biological process	IEP	HCCA
BP	GO:0048580	regulation of post-embryonic development	IEP	HCCA
BP	GO:0048582	positive regulation of post-embryonic development	IEP	HCCA
BP	GO:0048638	regulation of developmental growth	IEP	HCCA
BP	GO:0048831	regulation of shoot system development	IEP	HCCA
BP	GO:0050793	regulation of developmental process	IEP	HCCA
MF	GO:0051011	microtubule minus-end binding	IEP	HCCA
BP	GO:0051094	positive regulation of developmental process	IEP	HCCA
BP	GO:0051239	regulation of multicellular organismal process	IEP	HCCA
BP	GO:0051240	positive regulation of multicellular organismal process	IEP	HCCA
BP	GO:0051607	defense response to virus	IEP	HCCA
BP	GO:0051707	response to other organism	IEP	HCCA
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	HCCA
BP	GO:0065001	specification of axis polarity	IEP	HCCA
BP	GO:0070192	chromosome organization involved in meiotic cell cycle	IEP	HCCA
BP	GO:0070828	heterochromatin organization	IEP	HCCA
BP	GO:0070918	regulatory ncRNA processing	IEP	HCCA
BP	GO:0090066	regulation of anatomical structure size	IEP	HCCA
MF	GO:0097367	carbohydrate derivative binding	IEP	HCCA
CC	GO:0099080	supramolecular complex	IEP	HCCA
CC	GO:0099081	supramolecular polymer	IEP	HCCA
CC	GO:0099512	supramolecular fiber	IEP	HCCA
CC	GO:0099513	polymeric cytoskeletal fiber	IEP	HCCA
BP	GO:0140546	defense response to symbiont	IEP	HCCA
MF	GO:1901265	nucleoside phosphate binding	IEP	HCCA
BP	GO:1901987	regulation of cell cycle phase transition	IEP	HCCA
BP	GO:1901988	negative regulation of cell cycle phase transition	IEP	HCCA
BP	GO:1901990	regulation of mitotic cell cycle phase transition	IEP	HCCA
BP	GO:1901991	negative regulation of mitotic cell cycle phase transition	IEP	HCCA
BP	GO:1903047	mitotic cell cycle process	IEP	HCCA
BP	GO:2000026	regulation of multicellular organismal development	IEP	HCCA
BP	GO:2000241	regulation of reproductive process	IEP	HCCA
BP	GO:2000243	positive regulation of reproductive process	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR013498	Topo_IA_Znf	640	677
IPR010666	Znf_GRF	805	844
IPR013497	Topo_IA_cen	172	592
IPR006171	TOPRIM_domain	12	155

External Links

No external refs found!

AT5G63920 (AtTOP3alpha, TOP3A)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation